N6-methyladenosine (m6A) reader Pho92 is recruited co-transcriptionally and couples translation to mRNA decay to promote meiotic fitness in yeast

N6-methyladenosine (m6A) reader Pho92 is recruited co-transcriptionally and couples translation to mRNA decay to promote meiotic fitness in yeast

N6- methyladenosine (m6A) RNA modification impacts mRNA fate primarily via reader proteins, which dictate processes in development, stress, and disease. Yet little is known about m6A function in Saccharomyces cerevisiae, which occurs solely during early meiosis. Here, we perform a multifaceted analy...

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Bibliographic Details
Main Authors: Radhika A Varier, Theodora Sideri, Charlotte Capitanchik, Zornitsa Manova, Enrica Calvani, Alice Rossi, Raghu R Edupuganti, Imke Ensinck, Vincent WC Chan, Harshil Patel, Joanna Kirkpatrick, Peter Faull, Ambrosius P Snijders, Michiel Vermeulen, Markus Ralser, Jernej Ule, Nicholas M Luscombe, Folkert J van Werven
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-11-01
Series:eLife
Subjects:
m6A
RNA decay
Pho92
YTH
meiosis
translation
Online Access:https://elifesciences.org/articles/84034

Internet

https://elifesciences.org/articles/84034

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