NLRC5 potentiates anti-tumor CD8+ T cells responses by activating interferon-β in endometrial cancer

NLRC5 potentiates anti-tumor CD8+ T cells responses by activating interferon-β in endometrial cancer

Objectives: NLR family CARD domain containing 5 (NLRC5) could promote major histocompatibility complex class I (MHC-I)-dependent CD8+ T cell-mediated anticancer immunity. In this study, the immunosurveillance role and underlying mechanisms of NLRC5 in endometrial cancer (EC) were characterized. Meth...

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Bibliographic Details
Main Authors: Jing Zhang, Bao Guo, Jia-Hua Chen, Xiao-Jing Liu, Jun-Hui Zhang, Hai-Qing Zhu, Wen-Yan Wang, Zhen-Hai Tang, Bing Wei, Yun-Xia Cao, Lei Zhan
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Translational Oncology
Subjects:
Endometrial cancer, NLR family CARD domain-containing 5
Interferon-β
CD8+ T cells
Immunotherapy
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523323001286

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http://www.sciencedirect.com/science/article/pii/S1936523323001286

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