Endo‐lysosomal protein concentrations in CSF from patients with frontotemporal dementia caused by CHMP2B mutation

Endo‐lysosomal protein concentrations in CSF from patients with frontotemporal dementia caused by CHMP2B mutation

Abstract Introduction Increasing evidence implicates proteostatic dysfunction as an early event in the development of frontotemporal dementia (FTD). This study aimed to explore potential cerebrospinal fluid (CSF) biomarkers associated with the proteolytic systems in genetic FTD caused by CHMP2B muta...

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Bibliographic Details
Main Authors: Anders Toft, Simon Sjödin, Anja Hviid Simonsen, Patrick Ejlerskov, Peter Roos, Christian Sandøe Musaeus, Emil Elbæk Henriksen, Troels Tolstrup Nielsen, Ann Brinkmalm, Kaj Blennow, Henrik Zetterberg, Jørgen Erik Nielsen
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Subjects:
amyloid precursor protein
biomarkers
cathepsin B
cerebrospinal fluid
complement C9
frontotemporal dementia
Online Access:https://doi.org/10.1002/dad2.12402

Internet

https://doi.org/10.1002/dad2.12402

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