Improved mitochondrial function with diet-induced increase in either docosahexaenoic acid or arachidonic acid in membrane phospholipids.

Improved mitochondrial function with diet-induced increase in either docosahexaenoic acid or arachidonic acid in membrane phospholipids.

Mitochondria can depolarize and trigger cell death through the opening of the mitochondrial permeability transition pore (MPTP). We recently showed that an increase in the long chain n3 polyunsaturated fatty acids (PUFA) docosahexaenoic acid (DHA; 22:6n3) and depletion of the n6 PUFA arachidonic aci...

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Bibliographic Details
Main Authors: Ramzi J Khairallah, Junhwan Kim, Karen M O'Shea, Kelly A O'Connell, Bethany H Brown, Tatiana Galvao, Caroline Daneault, Christine Des Rosiers, Brian M Polster, Charles L Hoppel, William C Stanley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3316678?pdf=render

Internet

http://europepmc.org/articles/PMC3316678?pdf=render

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