USP18 directly regulates Snail1 protein through ubiquitination pathway in colorectal cancer

USP18 directly regulates Snail1 protein through ubiquitination pathway in colorectal cancer

Abstract Background Colorectal cancer (CRC) is one of the most common digestive malignant tumors in the world. Ubiquitin-specific peptidase 18 (USP18) plays a regulatory role in tumorigenesis, and abnormal expression of Snail1 is also believed to be related to tumorigenesis. However, whether USP18 c...

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Bibliographic Details
Main Authors: Fakun Huang, Chengying Zheng, Longkai Huang, Changqing Lin, Jiaxing Wang
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Cancer Cell International
Subjects:
Colorectal cancer
EMT
Snail1
USP18
qRT-PCR
Online Access:http://link.springer.com/article/10.1186/s12935-020-01442-1

Internet

http://link.springer.com/article/10.1186/s12935-020-01442-1

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