Smad2/3 signaling involved in urotensin II-induced phenotypic differentiation, collagen synthesis and migration of rat aortic adventitial fibroblasts

Objective. To investigate whether Smad2/3 signaling is involved in urotensin II (UII) induced activation of aortic adventitial fibroblasts. Materials and Methods. Growth-arrested adventitial fibroblasts were stimulated with UII in the presence or absence of urotensin II receptor (UT) antagonist SB7...

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Bibliographic Details
Main Authors: Weizhao Lin, Xu Yang, Fan Zheng, Jianshe Yang, Yonggang Zhang
Format: Article
Language:English
Published: PAGEPress Publications 2023-08-01
Series:Italian Journal of Medicine
Subjects:
Online Access:https://italjmed.org/index.php/ijm/article/view/1637