Yeast proteinopathy models: a robust tool for deciphering the basis of neurodegeneration

Protein quality control or proteostasis is an essential determinant of basic cell health and aging. Eukaryotic cells have evolved a number of proteostatic mechanisms to ensure that proteins retain functional conformation, or are rapidly degraded when proteins misfold or self-aggregate. Disruption of...

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Bibliographic Details
Main Authors: Amit Shrestha, Lynn A. Megeney
Format: Article
Language:English
Published: Shared Science Publishers OG 2015-11-01
Series:Microbial Cell
Subjects:
Online Access:http://microbialcell.com/researcharticles/yeast-proteinopathy-models-a-robust-tool-for-deciphering-the-basis-of-neurodegeneration/