Automated computation of nerve fibre inclinations from 3D polarised light imaging measurements of brain tissue

Abstract The method 3D polarised light imaging (3D-PLI) measures the birefringence of histological brain sections to determine the spatial course of nerve fibres (myelinated axons). While the in-plane fibre directions can be determined with high accuracy, the computation of the out-of-plane fibre in...

Full description

Bibliographic Details
Main Authors: Miriam Menzel, Jan A. Reuter, David Gräßel, Irene Costantini, Katrin Amunts, Markus Axer
Format: Article
Language:English
Published: Nature Portfolio 2022-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-08140-0