DNA Backbone Sulfur-Modification Expands Microbial Growth Range under Multiple Stresses by its anti-oxidation function

Abstract DNA phosphorothioate (PT) modification is a sulfur modification on the backbone of DNA introduced by the proteins DndA-E. It has been detected within many bacteria isolates and metagenomic datasets, including human pathogens, and is considered to be widely distributed in nature. However, li...

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Bibliographic Details
Main Authors: Yan Yang, Guanpeng Xu, Jingdan Liang, Ying He, Lei Xiong, Hui Li, Douglas Bartlett, Zixin Deng, Zhijun Wang, Xiang Xiao
Format: Article
Language:English
Published: Nature Portfolio 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-02445-1