MSI2 deficiency in ILC3s attenuates DSS-induced colitis by affecting the intestinal microbiota

MSI2 deficiency in ILC3s attenuates DSS-induced colitis by affecting the intestinal microbiota

BackgroundThe etiology and pathogenesis of inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn’s disease (CD), are generally believed to be related to immune dysfunction and intestinal microbiota disorder. However, the exact mechanism is not yet fully understood. The pathol...

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Bibliographic Details
Main Authors: Nengneng Li, Shiquan Xu, Shuaishuai Zhang, Qiang Zhu, Xiaole Meng, Wenbin An, Baoqing Fu, Mengya Zhong, Yan Yang, Zeyang Lin, Xueni Liu, Junjie Xia, Jie Wang, Tingting You, Changxiu Yan, Huamei Tang, Guohong Zhuang, Zhihai Peng
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
inflammatory bowel disease
intestinal microbiota
Musashi2
group 3 innate lymphoid cells
Lactobacillaceae
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.963379/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.963379/full

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