Xbp1 and Brachyury establish an evolutionarily conserved subcircuit of the notochord gene regulatory network

Gene regulatory networks coordinate the formation of organs and structures that compose the evolving body plans of different organisms. We are using a simple chordate model, the Ciona embryo, to investigate the essential gene regulatory network that orchestrates morphogenesis of the notochord, a str...

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Bibliographic Details
Main Authors: Yushi Wu, Arun Devotta, Diana S José-Edwards, Jamie E Kugler, Lenny J Negrón-Piñeiro, Karina Braslavskaya, Jermyn Addy, Jean-Pierre Saint-Jeannet, Anna Di Gregorio
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-01-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/73992