Lumican accumulates with fibrillar collagen in fibrosis in hypertrophic cardiomyopathy

Lumican accumulates with fibrillar collagen in fibrosis in hypertrophic cardiomyopathy

Abstract Aims Familial hypertrophic cardiomyopathy (HCM) is the most common form of inherited cardiac disease. It is characterized by myocardial hypertrophy and diastolic dysfunction, and can lead to severe heart failure, arrhythmias, and sudden cardiac death. Cardiac fibrosis, defined by excessive...

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Bibliographic Details
Main Authors: Chloe Rixon, Kristine Andreassen, Xin Shen, Pugazendhi Murugan Erusappan, Vibeke Marie Almaas, Sheryl Palmero, Christen Peder Dahl, Thor Ueland, Ivar Sjaastad, William Edward Louch, Mathis Korseberg Stokke, Theis Tønnessen, Geir Christensen, Ida Gjervold Lunde
Format: Article
Language:English
Published: Wiley 2023-04-01
Series:ESC Heart Failure
Subjects:
Heart
HCM
SLRPs
Extracellular matrix
ECM remodelling
dSTORM
Online Access:https://doi.org/10.1002/ehf2.14234

Internet

https://doi.org/10.1002/ehf2.14234

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