Th1-dominant cytokine responses in kidney patients after COVID-19 vaccination are associated with poor humoral responses

Abstract Cytokines are regulators of the immune response against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). However, the contribution of cytokine-secreting CD4+ and CD8+ memory T cells to the SARS-CoV-2-specific humoral immune response in immunocompromised kidney patients is unkno...

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Bibliographic Details
Main Authors: Yvette den Hartog, S. Reshwan K. Malahe, Wim J. R. Rietdijk, Marjolein Dieterich, Lennert Gommers, Daryl Geers, Susanne Bogers, Debbie van Baarle, Dimitri A. Diavatopoulos, A. Lianne Messchendorp, Renate G. van der Molen, Ester B. M. Remmerswaal, Frederike J. Bemelman, Ron T. Gansevoort, Luuk B. Hilbrands, Jan-Stephan Sanders, Corine H. GeurtsvanKessel, Marcia M. L. Kho, Marlies E. J. Reinders, Rory D. de Vries, Carla C. Baan, on behalf of RECOVAC Consortium
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-023-00664-4