Convergent lines of evidence support BIN1 as a risk gene of Alzheimer’s disease
Abstract Genome-wide association studies (GWAS) have identified several susceptibility loci of Alzheimer’s disease (AD), which were mainly located in noncoding regions of the genome. Meanwhile, the putative biological mechanisms underlying AD susceptibility loci were still unclear. At present, ident...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-01-01
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Series: | Human Genomics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s40246-021-00307-6 |