Convergent lines of evidence support BIN1 as a risk gene of Alzheimer’s disease

Abstract Genome-wide association studies (GWAS) have identified several susceptibility loci of Alzheimer’s disease (AD), which were mainly located in noncoding regions of the genome. Meanwhile, the putative biological mechanisms underlying AD susceptibility loci were still unclear. At present, ident...

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Bibliographic Details
Main Authors: Jin Zhu, Xia Liu, Hongtao Yin, Yan Gao, Hao Yu
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Human Genomics
Subjects:
Online Access:https://doi.org/10.1186/s40246-021-00307-6