α-Linolenic acid induces clearance of Tau seeds via Actin-remodeling in Microglia
Abstract Alzheimer’s disease (AD) is known by characteristic features, extracellular burden of amyloid-β and intracellular neuronal Tau. Microglia, the innate immune cell of the brain has the ability to clear the burden of accumulated proteins via phagocytosis. But the excessive proinflammatory cyto...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Springer
2021-02-01
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| Series: | Molecular Biomedicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s43556-021-00028-1 |