Ubiquitylation of cyclin C by HACE1 regulates cisplatin‐associated sensitivity in gastric cancer

Abstract Background Cyclin C (CCNC) was reported to take part in regulating mitochondria‐derived oxidative stress under cisplatin stimulation. However, its effect in gastric cancer is unknown. This study aimed to investigate the role of cyclin C and its ubiquitylation in regulating cisplatin resista...

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Bibliographic Details
Main Authors: Hong‐yue Jiang, Ying‐ling Chen, Xing‐xing Xu, Chuan‐yin Li, Yun Chen, Dong‐ping Li, Xiao‐qing Zeng, Hong Gao
Format: Article
Language:English
Published: Wiley 2022-03-01
Series:Clinical and Translational Medicine
Subjects:
Online Access:https://doi.org/10.1002/ctm2.770