GM-CSF, Flt3-L and IL-4 affect viability and function of conventional dendritic cell types 1 and 2

GM-CSF, Flt3-L and IL-4 affect viability and function of conventional dendritic cell types 1 and 2

Conventional type 1 dendritic cells (cDC1) and conventional type 2 dendritic cells (cDC2) have attracted increasing attention as alternatives to monocyte-derived dendritic cells (moDCs) in cancer immunotherapy. Use of cDCs for therapy has been hindered by their low numbers in peripheral blood. In th...

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Bibliographic Details
Main Authors: Seyed Mohammad Lellahi, Waqas Azeem, Yaping Hua, Benjamin Gabriel, Kristin Paulsen Rye, Håkon Reikvam, Karl-Henning Kalland
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
myeloid dendritic cells
conventional dendritic cells
DC viability
DC apoptosis
DC death
cytokine
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1058963/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1058963/full

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