Variable allelic expression of imprinted genes at the Peg13, Trappc9, Ago2 cluster in single neural cells

Variable allelic expression of imprinted genes at the Peg13, Trappc9, Ago2 cluster in single neural cells

Genomic imprinting is an epigenetic process through which genes are expressed in a parent-of-origin specific manner resulting in mono-allelic or strongly biased expression of one allele. For some genes, imprinted expression may be tissue-specific and reliant on CTCF-influenced enhancer-promoter inte...

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Bibliographic Details
Main Authors: Michael Claxton, Michela Pulix, Michelle K. Y. Seah, Ralph Bernardo, Peng Zhou, Sultan Aljuraysi, Triantafillos Liloglou, Philippe Arnaud, Gavin Kelsey, Daniel M. Messerschmidt, Antonius Plagge
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
genomic imprinting
allelic expression
single-cell analysis
neurosphere
neural stem cell
Peg13
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.1022422/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2022.1022422/full

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