M1 muscarinic receptor activation protects neurons from β-amyloid toxicity. A role for Wnt signaling pathway

Amyloid-β-peptide (Aβ) deposits are one of the hallmark features of Alzheimer's disease. Signal transduction alterations are implicate in the neuronal responses to Aβ, which include neurotransmitter systems and pathways involved in the maintenance of the nervous system. In this context, we have...

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Bibliographic Details
Main Authors: Ginny G. Farías, Juan A. Godoy, Félix Hernández, Jesús Avila, Abraham Fisher, Nibaldo C. Inestrosa
Format: Article
Language:English
Published: Elsevier 2004-11-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996104001536