Central Versus Peripheral Drug Exposure Ratio, a Key Differentiator for Siponimod Over Fingolimod?

Abstract Introduction Siponimod, a potent and selective sphingosine-1-phosphate (S1P1,5) agonist, is the only therapeutic agent that has shown efficacy against disability progression, decline in cognitive processing speed, total brain volume loss, gray matter atrophy and signs of demyelination in pa...

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Bibliographic Details
Main Authors: Marc Bigaud, Pamela Ramseier, Sarah Tisserand, Meike Lang, Beatrice Urban, Christian Beerli, Göril Karlsson
Format: Article
Language:English
Published: Adis, Springer Healthcare 2023-05-01
Series:Neurology and Therapy
Subjects:
Online Access:https://doi.org/10.1007/s40120-023-00487-4