Effects of Combinations of Untranslated-Region Sequences on Translation of mRNA

mRNA-based therapeutics have been found to be a promising treatment strategy in immunotherapy, gene therapy, and cancer treatments. Effectiveness of mRNA therapeutics depends on the level and duration of a desired protein’s expression, which is determined by various <i>cis</i>- and <i...

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Bibliographic Details
Main Authors: Anna Kirshina, Olga Vasileva, Dmitry Kunyk, Kristina Seregina, Albert Muslimov, Roman Ivanov, Vasiliy Reshetnikov
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/13/11/1677