Effects of Combinations of Untranslated-Region Sequences on Translation of mRNA

Effects of Combinations of Untranslated-Region Sequences on Translation of mRNA

mRNA-based therapeutics have been found to be a promising treatment strategy in immunotherapy, gene therapy, and cancer treatments. Effectiveness of mRNA therapeutics depends on the level and duration of a desired protein’s expression, which is determined by various <i>cis</i>- and <i...

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Bibliographic Details
Main Authors:	Anna Kirshina, Olga Vasileva, Dmitry Kunyk, Kristina Seregina, Albert Muslimov, Roman Ivanov, Vasiliy Reshetnikov
Format:	Article
Language:	English
Published:	MDPI AG 2023-11-01
Series:	Biomolecules
Subjects:	5′UTR 3′UTR mRNA therapeutics translation efficiency RNA stability
Online Access:	https://www.mdpi.com/2218-273X/13/11/1677

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