Galactomannan-Decorated Lipidic Nanocarrier for Gene Supplementation Therapy in Fabry Disease

Galactomannan-Decorated Lipidic Nanocarrier for Gene Supplementation Therapy in Fabry Disease

Gene supplementation therapy with plasmid DNA (pDNA) represents one of the most promising strategies for the treatment of monogenic diseases such as Fabry disease (FD). In the present work, we developed a solid lipid nanoparticles (SLN)-based non-viral vector with a size below 100 nm, and decorated...

Full description

Bibliographic Details
Main Authors: Julen Rodríguez-Castejón, Itziar Gómez-Aguado, Marina Beraza-Millor, María Ángeles Solinís, Ana del Pozo-Rodríguez, Alicia Rodríguez-Gascón
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Nanomaterials
Subjects:
advanced therapies
Fabry disease
galactomannan
gene augmentation
intravenous administration
non-viral vectors
Online Access:https://www.mdpi.com/2079-4991/12/14/2339

Internet

https://www.mdpi.com/2079-4991/12/14/2339

Similar Items