Cytotoxicity of VEGF<sub>121</sub>/rGel on vascular endothelial cells resulting in inhibition of angiogenesis is mediated via VEGFR-2

Cytotoxicity of VEGF<sub>121</sub>/rGel on vascular endothelial cells resulting in inhibition of angiogenesis is mediated via VEGFR-2

<p>Abstract</p> <p>Background</p> <p>The fusion protein VEGF<sub>121</sub>/rGel composed of the growth factor VEGF<sub>121 </sub>and the plant toxin gelonin targets the tumor neovasculature and exerts impressive anti-vascular effects. We have pre...

Full description

Bibliographic Details
Main Authors: Hittelman Walter N, Cheung Lawrence H, Kim Sehoon, Xu Jing, Ramdas Latha, Gomez-Manzano Candelaria, Ran Sophia, Mohamedali Khalid A, Zhang Wei, Waltenberger Johannes, Thorpe Philip E, Rosenblum Michael G
Format: Article
Language:English
Published: BMC 2011-08-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/11/358

Internet

http://www.biomedcentral.com/1471-2407/11/358

Similar Items