Association between genetic polymorphism in tumor necrosis factor-alpha gene and adverse effects of etanercept in rheumatoid arthritis patients

Background. Gene polymorphisms affect etanercept’s pharmacokinetics, pharmacodynamics, and side effects. This effect is evidenced by the extensive genetic variation in the drug’s targets. Objectives. This study aims to find the association between different genotypes of the promoter region of the TN...

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Bibliographic Details
Main Authors: Samer Imad Mohammed, Munaf Hashim Zalzala, Faiq Isho Gorial
Format: Article
Language:English
Published: Amaltea Medical Publishing House 2023-09-01
Series:Romanian Journal of Rheumatology
Subjects:
Online Access:https://rjr.com.ro/articles/2023.3/RJR_2023_3_Art-03.pdf