466 Development of a novel tocotrienol analogue, tocoflexol, as a radiomitigator

OBJECTIVES/GOALS: We have designed an analogue of the Vitamin E tocotrienols called tocoflexol, which improves their pharmacokinetic limitations to make it an effective radiation medical countermeasure. Our goal is to demonstrate that tocoflexol is an effective radiomitigator in vivo when administer...

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Bibliographic Details
Main Authors: Shivangi Shrimali, Awantika Singh, Rajeshkumar Manian, Shraddha Thakkar, Darin E. Jones, Nukhet Aykin-Burns, Philip Breen, Cesar M. Compadre
Format: Article
Language:English
Published: Cambridge University Press 2023-04-01
Series:Journal of Clinical and Translational Science
Online Access:https://www.cambridge.org/core/product/identifier/S2059866123004855/type/journal_article