Signaling through cholesterol esterification: a new pathway for the cholecystokinin 2 receptor involved in cell growth and invasion

Signaling through cholesterol esterification: a new pathway for the cholecystokinin 2 receptor involved in cell growth and invasion

Several studies indicate that cholesterol esterification is deregulated in cancers. The present study aimed to characterize the role of cholesterol esterification in proliferation and invasion of two tumor cells expressing an activated cholecystokinin 2 receptor (CCK2R). A significant increase in ch...

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Bibliographic Details
Main Authors: Michael R. Paillasse, Philippe de Medina, Guillaume Amouroux, Loubna Mhamdi, Marc Poirot, Sandrine Silvente-Poirot
Format: Article
Language:English
Published: Elsevier 2009-11-01
Series:Journal of Lipid Research
Subjects:
cholesteryl ester
acyl-CoA:cholesterol acyltransferase
constitutively active mutant
autocrine stimulation
G protein coupled receptor
gastrin receptor
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520306866

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http://www.sciencedirect.com/science/article/pii/S0022227520306866

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