Identification of a new genetic variant (G231N, E232T, N235D) of peptidylarginine deiminase from P. gingivalis in advanced periodontitis

Identification of a new genetic variant (G231N, E232T, N235D) of peptidylarginine deiminase from P. gingivalis in advanced periodontitis

Chronic periodontitis (CP), an inflammatory disease of periodontal tissues driven by a dysbiotic subgingival bacterial biofilm, is also associated with several systemic diseases, including rheumatoid arthritis (RA). Porphyromonas gingivalis, one of the bacterial species implicated in CP as a keyston...

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Main Authors: Grzegorz P. Bereta, Karolina Strzelec, Katarzyna Łazarz-Bartyzel, Agata Dziedzic-Kowalska, Zuzanna Nowakowska, Anna Krutyhołowa, Ewa Bielecka, Tomasz Kantyka, Aleksander M. Grabiec, Tomasz Kaczmarzyk, Maria Chomyszyn-Gajewska, Jan Potempa, Katarzyna Gawron
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Immunology
Subjects:
chronic periodontitis
P. gingivalis
virulence
peptidylarginine deiminase
polymorphic variant(s)
genetic variability
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1355357/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1355357/full

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