Four temporin-derived peptides exhibit antimicrobial and antibiofilm activities against methicillin-resistant Staphylococcus aureus

Four temporin-derived peptides exhibit antimicrobial and antibiofilm activities against methicillin-resistant Staphylococcus aureus

Temporin-GHa (GHa) was cloned from Hylarana guentheri, showing a weak antimicrobial activity. In order to improve its bactericidal efficacy, GHaR6R, GHaR7R, GHaR8R and GHaR9W were designed and synthesized. Compared to the parent peptide, the GHa-derived peptides show potent antimicrobial activities...

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Bibliographic Details
Main Authors: Tan Xiuchuan, Xie Shenghong, Jin Xiao, Zhu Ruiying, Wei Shuangshuang, Song Yanting, Xie Xi, Wang Rong, Li Lushuang, Wang Manchuriga, Zhang Yingxia
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2022-03-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
antimicrobial peptide
antibacterial activity
antibiofilm activity
methicillin-resistant <italic>Staphylococcus aureus</italic>
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2022013

Internet

https://www.sciengine.com/doi/10.3724/abbs.2022013

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