A CCHFV DNA vaccine protects against heterologous challenge and establishes GP38 as immunorelevant in mice
Abstract Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne virus that causes severe hemorrhagic fever disease in humans. Currently, no licensed CCHF vaccines exist, and the protective epitopes remain unclear. Previously, we tested a DNA vaccine expressing the M-segment glycoprotein precu...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-03-01
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| Series: | npj Vaccines |
| Online Access: | https://doi.org/10.1038/s41541-021-00293-9 |