Neurodegeneration with inflammation is accompanied by accumulation of iron and ferritin in microglia and neurons

Neurodegeneration with inflammation is accompanied by accumulation of iron and ferritin in microglia and neurons

Chronic inflammation in the substantia nigra (SN) accompanies conditions with progressive neurodegeneration. This inflammatory process contributes to gradual iron deposition that may catalyze formation of free-radical mediated damage, hence exacerbating the neurodegeneration. This study examined pro...

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Bibliographic Details
Main Authors: Maj Schneider Thomsen, Michelle Vandborg Andersen, Pia Rægaard Christoffersen, Malene Duedal Jensen, Jacek Lichota, Torben Moos
Format: Article
Language:English
Published: Elsevier 2015-09-01
Series:Neurobiology of Disease
Subjects:
Ferritin
Hepcidin
Iron
Microglia
Monocyte
Neurodegeneration
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996115000856

Internet

http://www.sciencedirect.com/science/article/pii/S0969996115000856

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