Acinetobacter baumannii Outer Membrane Protein A Induces Pulmonary Epithelial Barrier Dysfunction and Bacterial Translocation Through The TLR2/IQGAP1 Axis

Acinetobacter baumannii Outer Membrane Protein A Induces Pulmonary Epithelial Barrier Dysfunction and Bacterial Translocation Through The TLR2/IQGAP1 Axis

Pulmonary epithelial barrier dysfunction is a critical pathophysiological process in pneumonia and associated invasive infections, such as those caused by Acinetobacter baumannii. However, the mechanisms underlying A. baumannii-induced pulmonary epithelial barrier dysfunction and bacterial transloca...

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Bibliographic Details
Main Authors: Wang Zhang, Hua Zhou, Yan Jiang, Jintao He, Yue Yao, Jianfeng Wang, Xiaochen Liu, Sebastian Leptihn, Xiaoting Hua, Yunsong Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
Acinetobacter baumannii
outer membrane protein A
epithelial barrier
bacterial translocation
cytoskeleton
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.927955/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.927955/full

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