Activity of the Di-Substituted Urea-Derived Compound I-17 in <i>Leishmania</i> In Vitro Infections

Activity of the Di-Substituted Urea-Derived Compound I-17 in <i>Leishmania</i> In Vitro Infections

Protein synthesis has been a very rich target for developing drugs to control prokaryotic and eukaryotic pathogens. Despite the development of new drug formulations, treating human cutaneous and visceral <i>Leishmaniasis</i> still needs significant improvements due to the considerable si...

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Bibliographic Details
Main Authors: José Vitorino dos Santos, Jorge Mansur Medina, Karina Luiza Dias Teixeira, Daniel Marcos Julio Agostinho, Michael Chorev, Aurora Diotallevi, Luca Galluzzi, Bertal Huseyin Aktas, Ulisses Gazos Lopes
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Pathogens
Subjects:
Leishmaniasis
eIF2α
translation initiation
eIF2α kinase activators
di-substituted urea-derivatives
Online Access:https://www.mdpi.com/2076-0817/13/2/104

Internet

https://www.mdpi.com/2076-0817/13/2/104

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