DNA display selection of peptide ligands for a full-length human G protein-coupled receptor on CHO-K1 cells.

DNA display selection of peptide ligands for a full-length human G protein-coupled receptor on CHO-K1 cells.

The G protein-coupled receptors (GPCRs), which form the largest group of transmembrane proteins involved in signal transduction, are major targets of currently available drugs. Thus, the search for cognate and surrogate peptide ligands for GPCRs is of both basic and therapeutic interest. Here we des...

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Bibliographic Details
Main Authors: Nobuhide Doi, Natsuko Yamakawa, Hideaki Matsumoto, Yasutsugu Yamamoto, Tetsuya Nagano, Nobutaka Matsumura, Kenichi Horisawa, Hiroshi Yanagawa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3254644?pdf=render

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http://europepmc.org/articles/PMC3254644?pdf=render

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