Mutation profiling of cancer drivers in Brazilian colorectal cancer

Abstract The molecular basis of colorectal cancer (CRC) can guide patient prognosis and therapy. In Brazil, knowledge on the CRC mutation landscape is limited. Here, we investigated the mutation profile of 150 cancer-related genes by next-generation sequencing and associated with microsatellite inst...

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Bibliographic Details
Main Authors: Wellington dos Santos, Thais Sobanski, Ana Carolina de Carvalho, Adriane Feijó Evangelista, Marcus Matsushita, Gustavo Nóriz Berardinelli, Marco Antonio de Oliveira, Rui Manuel Reis, Denise Peixoto Guimarães
Format: Article
Language:English
Published: Nature Portfolio 2019-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-49611-1