[1, 8]-Naphthyridine derivatives as dual inhibitor of alkaline phosphatase and carbonic anhydrase

[1, 8]-Naphthyridine derivatives as dual inhibitor of alkaline phosphatase and carbonic anhydrase

Abstract [1,8]-Naphthyridine derivatives have been reported to possess important biological activities and may serve as attractive pharmacophores in the drug discovery process. [1,8]-Naphthyridine derivatives (1a-1l) were evaluated for inhibitory potential for isozymes of carbonic anhydrase (CA) and...

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Bibliographic Details
Main Authors: Salman Alrokayan, Tajamul Hussain, Salman Alamery, Arif Ahmed Mohammed, Abid Mahmood, Syeda Abida Ejaz, Peter Langer, Jamshed Iqbal
Format: Article
Language:English
Published: BMC 2023-10-01
Series:BMC Chemistry
Subjects:
Carbonic anhydrase
Alkaline phosphatase
[1, 8]-Naphthyridine derivatives
Simulation studies
DFT studies
Online Access:https://doi.org/10.1186/s13065-023-01052-8

Internet

https://doi.org/10.1186/s13065-023-01052-8

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