Production of IL1-beta by ovarian cancer cells induces mesothelial cell beta1-integrin expression facilitating peritoneal dissemination

Production of IL1-beta by ovarian cancer cells induces mesothelial cell beta1-integrin expression facilitating peritoneal dissemination

<p>Abstract</p> <p>Background</p> <p>A crucial step in the metastatic spread of ovarian cancer (OC) is the adhesion and implantation of tumor cells to the peritoneal mesothelium. In order to study this step in the cascade, we derived a pro-metastatic human ovarian carci...

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Bibliographic Details
Main Authors: Watanabe Takafumi, Hashimoto Toshihiro, Sugino Takashi, Soeda Shu, Nishiyama Hiroshi, Morimura Yutaka, Yamada Hidekazu, Goodison Steve, Fujimori Keiya
Format: Article
Language:English
Published: BMC 2012-02-01
Series:Journal of Ovarian Research
Subjects:
ovarian cancer
peritoneal dissemination
IL-1β
β1 integrin
mesothelial cell
Online Access:http://www.ovarianresearch.com/content/5/1/7

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http://www.ovarianresearch.com/content/5/1/7

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