Unexpected Synthesis, Single-Crystal X-ray Structure, Anticancer Activity, and Molecular Docking Studies of Certain 2–((Imidazole/Benzimidazol–2–yl)thio)–1–arylethanones

Unexpected Synthesis, Single-Crystal X-ray Structure, Anticancer Activity, and Molecular Docking Studies of Certain 2–((Imidazole/Benzimidazol–2–yl)thio)–1–arylethanones

In connection with our research program concerning development of novel effective benzimidazole-based anticancer candidates, herein we describe a new unexpected synthetic route to obtain a series of 2–((imidazole/benzimidazol2–yl)thio)1–arylethanones endowed with promising anti-breast cancer and Cyc...

Full description

Bibliographic Details
Main Authors: Tarfah Al-Warhi, Mohamed A. Said, Mahmoud A. El Hassab, Nada Aljaeed, Hazem A. Ghabour, Hadia Almahli, Wagdy M. Eldehna, Hatem A. Abdel-Aziz
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Crystals
Subjects:
imidazole/benzimidazole
<i>β</i>-keto esters
anticancer
cdk2 inhibitors
single-crystal X-ray analyses
Online Access:https://www.mdpi.com/2073-4352/10/6/446

Internet

https://www.mdpi.com/2073-4352/10/6/446

Similar Items