Investigating the relationship between the SNCA gene and cognitive abilities in idiopathic Parkinson’s disease using machine learning

Investigating the relationship between the SNCA gene and cognitive abilities in idiopathic Parkinson’s disease using machine learning

Abstract Cognitive impairments are prevalent in Parkinson’s disease (PD), but the underlying mechanisms of their development are unknown. In this study, we aimed to predict global cognition (GC) in PD with machine learning (ML) using structural neuroimaging, genetics and clinical and demographic cha...

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Bibliographic Details
Main Authors: Mehrafarin Ramezani, Pauline Mouches, Eunjin Yoon, Deepthi Rajashekar, Jennifer A. Ruskey, Etienne Leveille, Kristina Martens, Mekale Kibreab, Tracy Hammer, Iris Kathol, Nadia Maarouf, Justyna Sarna, Davide Martino, Gerald Pfeffer, Ziv Gan-Or, Nils D. Forkert, Oury Monchi
Format: Article
Language:English
Published: Nature Portfolio 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-84316-4

Internet

https://doi.org/10.1038/s41598-021-84316-4

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