Characterization of B-cell and T-cell responses to a tetravalent dengue purified inactivated vaccine in healthy adults

Abstract The increasing global impact of dengue underscores the need for a dengue virus (DENV) vaccine. We assessed B-cell and T-cell responses following vaccination with four formulations of a tetravalent dengue purified inactivated vaccine (DPIV) in dengue-primed and dengue-naive adults from two s...

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Bibliographic Details
Main Authors: Heather Friberg, Morgan Gargulak, Amanda Kong, Leyi Lin, Luis J. Martinez, Alexander C. Schmidt, Robert M. Paris, Richard G. Jarman, Clemente Diaz, Stephen J. Thomas, Philippe Moris, Jeffrey R. Currier
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-022-00537-2