Identification of Heme Oxygenase-1 as a Putative DNA-Binding Protein

Identification of Heme Oxygenase-1 as a Putative DNA-Binding Protein

Heme oxygenase-1 (HO-1) is a rate-limiting enzyme in degrading heme into biliverdin and iron. HO-1 can also enter the nucleus and regulate gene transcription independent of its enzymatic activity. Whether HO-1 can alter gene expression through direct binding to target DNA remains unclear. Here, we p...

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Bibliographic Details
Main Authors: Alejandro Scaffa, George A. Tollefson, Hongwei Yao, Salu Rizal, Joselynn Wallace, Nathalie Oulhen, Jennifer F. Carr, Katy Hegarty, Alper Uzun, Phyllis A. Dennery
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Antioxidants
Subjects:
heme oxygenase-1
DNA binding
proteinarium
3D structural modeling
Online Access:https://www.mdpi.com/2076-3921/11/11/2135

Internet

https://www.mdpi.com/2076-3921/11/11/2135

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