RATIONAL APPROACHES FOR ENGINEERING NOVEL FUNCTIONALITIES IN CARBON-CARBON BOND FORMING ENZYMES

Enzymes that catalyze carbon-carbon bond formation can be exploited as biocatalyst for synthetic organic chemistry. However, natural enzymes frequently do not possess the required properties or specificities to catalyze industrially useful transformations. This mini-review describes recent work usin...

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Bibliographic Details
Main Authors: Perrin Baker, Stephen Y.K. Seah
Format: Article
Language:English
Published: Elsevier 2012-09-01
Series:Computational and Structural Biotechnology Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037014600817