Deep sequencing analysis of HBV genotype shift and correlation with antiviral efficiency during adefovir dipivoxil therapy.

Deep sequencing analysis of HBV genotype shift and correlation with antiviral efficiency during adefovir dipivoxil therapy.

Viral genotype shift in chronic hepatitis B (CHB) patients during antiviral therapy has been reported, but the underlying mechanism remains elusive.38 CHB patients treated with ADV for one year were selected for studying genotype shift by both deep sequencing and Sanger sequencing method.Sanger sequ...

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Bibliographic Details
Main Authors: Yuwei Wang, Xuefeng Shan, Zhi Liang, Youlan Shan, Wenxiang Huang, Dazhi Zhang, Aizhong Zen, Xin Zhou, Yao Zhao, Xuyang Gong, Ge Xu, Xiuyu Zhang, Juan Chen, Ailong Huang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4482366?pdf=render

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http://europepmc.org/articles/PMC4482366?pdf=render

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