ARRDC5 expression is conserved in mammalian testes and required for normal sperm morphogenesis

Abstract In sexual reproduction, sperm contribute half the genomic material required for creation of offspring yet core molecular mechanisms essential for their formation are undefined. Here, the α-arrestin molecule arrestin-domain containing 5 (ARRDC5) is identified as an essential regulator of mam...

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Bibliographic Details
Main Authors: Mariana I. Giassetti, Deqiang Miao, Nathan C. Law, Melissa J. Oatley, Julie Park, LeeLa D. Robinson, Lisette A. Maddison, Miranda L. Bernhardt, Jon M. Oatley
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-37735-y