Pathophysiological mechanisms of statin‐associated myopathies: possible role of the ubiquitin‐proteasome system

Background Statins are the cornerstone of pharmacotherapy for atherosclerotic cardiovascular disease. While these drugs are generally safe, treatment adherence is not optimal in a considerable proportion of patients because of the adverse effects on skeletal muscles in the forms of myopathy, myalgia...

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Main Authors: Amirhossein Sahebkar, Arrigo F.G. Cicero, Paolo Di Giosia, Irene Pomilio, Cosimo Andrea Stamerra, Paolo Giorgini, Claudio Ferri, Stephan vonHaehling, Maciej Banach, Tannaz Jamialahmadi
Format: Article
Language:English
Published: Wiley 2020-10-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Online Access:https://doi.org/10.1002/jcsm.12579