Construction of a Chikungunya Virus, Replicon, and Helper Plasmids for Transfection of Mammalian Cells

The genome of Alphaviruses can be modified to produce self-replicating RNAs and virus-like particles, which are useful virological tools. In this work, we generated three plasmids for the transfection of mammalian cells: an infectious clone of Chikungunya virus (CHIKV), one that codes for the struct...

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Bibliographic Details
Main Authors: Mayra Colunga-Saucedo, Edson I. Rubio-Hernandez, Miguel A. Coronado-Ipiña, Sergio Rosales-Mendoza, Claudia G. Castillo, Mauricio Comas-Garcia
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/15/1/132