Safety assessment, radioiodination and preclinical evaluation of antinuclear antibody as novel medication for prostate cancer in mouse xenograft model

Abstract This study aims to provide in vitro and in vivo data to support the utilization of antinuclear antibodies (ANAs) as novel tools for the diagnosis and treatment of prostate cancers. The hematological, biochemical, and histological toxicities of ANAs were assessed at the doses of 5 and 50 μg...

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Main Authors: Thu Minh Chau Nguyen, Lu Duc Chinh Hoang, Thi Khanh Giang Nguyen, Thi Ngoc Nguyen, Quang Chien Nguyen, Thanh Binh Nguyen, Ho Hong Quang Dang, Van Cuong Bui, Thanh Minh Pham, Thi Thu Nguyen
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-45984-6