Time-Dependent ROC Curve Analysis for Assessing the Capability of Radiation-Induced CD8 T-Lymphocyte Apoptosis to Predict Late Toxicities after Adjuvant Radiotherapy of Breast Cancer Patients

Time-Dependent ROC Curve Analysis for Assessing the Capability of Radiation-Induced CD8 T-Lymphocyte Apoptosis to Predict Late Toxicities after Adjuvant Radiotherapy of Breast Cancer Patients

Late fibrosis can occur in breast cancer patients treated with curative-intent radiotherapy. Predicting this toxicity is of clinical interest in order to adapt the irradiation dose delivered. Radiation-induced CD8 T-lymphocyte apoptosis (RILA) had been proven to be associated with less grade ≥2 late...

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Bibliographic Details
Main Authors: Célia Touraine, Audrey Winter, Florence Castan, David Azria, Sophie Gourgou
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Cancers
Subjects:
ROC curve
time-dependent AUC
biomarker
prediction
radiotherapy
breast fibrosis
Online Access:https://www.mdpi.com/2072-6694/15/19/4676

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https://www.mdpi.com/2072-6694/15/19/4676

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