Social isolation induces hyperactivity and exploration in aged female mice.

Prolonged social isolation is associated with poor physical and mental health outcomes, findings observed in both humans, and rodent models of isolation. Humans, like mice, may engage in enhanced exploratory and social behaviour following isolation, which may protect against subsequent cognitive dec...

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Bibliographic Details
Main Authors: D Gregory Sullens, Kayla Gilley, Kendall Jensen, Elisabeth Vichaya, Sara L Dolan, Melanie J Sekeres
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0245355