CRNDE enhances the expression of MCM5 and proliferation in acute myeloid leukemia KG-1a cells by sponging miR-136-5p

Abstract The long-noncoding RNA colorectal neoplasia differentially expressed (CRNDE) gene has been considered to be crucial in tumor malignancy. Although CRNDE is highly expressed in acute myeloid leukemia (AML), its mechanism of action remains unknown. In this study, GEPIA and qRT-PCR were perform...

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Bibliographic Details
Main Authors: Chen Liu, Liang Zhong, Chenlan Shen, Xuan Chu, Xu Luo, Lihua Yu, Jiao Ye, Ling Xiong, Wenran Dan, Jian Li, Beizhong Liu
Format: Article
Language:English
Published: Nature Portfolio 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-96156-3